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Low volume blood collection and sample elution for serology testing

29 Ideas
17 Votes
213 Comments
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Serology testing largely depends on formal phlebotomy. In order to expand serology testing into the broader community, we need to able to collect blood without the need for phlebotomy.

We are looking for examples where small volume blood collection, coupled with elution where relevant, can be used for COVID-19 antibody testing for immediate or very rapid roll out.

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A: Not for current challenges
E: A connection is helpful

Helping to establish when immunity occurs

Whilst many people are being tested for presence of RNA and for antibody production, select some populations for repeated testing of both and monitor symptoms and clinical signs and other evidence of likely source(s) of infection/ re-infection. This with a view to elucidating when immunity occurs. Maybe do the same in a control group, age and sex matched, to help interpret the findings. Groups that could followed include clinical staff, and long term care facility patients. This could...

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A: Not for current challenges

COMPLETE COLLECTION AND SEROLOGY MEASUREMENT SYSTEM

An Australian company Atomo Diagnostics have an interesting lateral flow system which has a built in lancet, blood transfer, diluent  and  serology strips could be inserted to  make a very user friendly device.  Currently used in third world for malaria.

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A: Not for current challenges

A revolutionary COVID-19 (S glycoprotein) rapid test strip

We have developed a revolutionary COVID-19 (S glycoprotein) rapid test strip , which is completely different from nucleic acid detection and antibodies detection.  The advantages of this new antigen (S protein) detection strip are: 1. Rapid direct detection: c an detect the presence of virus directly and get the result within 5-15 minutes . 2. Non-invasive detection: innovative use of respiratory secretions (nasal mucus, sputum) and stool testing,. 3. High specificity: the...

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4
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A: Not for current challenges

Fingerstick blood collection and preservation

6 drops of blood are collected in the Hem-Col tube. In the tube a preservation fluid preserves the blood for upto 5 days. Blood can be send by regular postal services to the lab. In the lab the blood can be analysed on the usual clinical chemistry, immunchemistry and hematology analysers. By measuring an internal standard the results can be corrected for dilution by the preservation fluid. 

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A: Not for current challenges

Novel Blood Collection Device that Enables Small-Volume Capillary Blood Collection for Diagnostic Testing

BD would like to engage in exploratory discussions about a novel, easy to use blood collection device, that is currently in development. BD in partnership with Babson Diagnostics has developed a revolutionary capillary blood collection system that eliminates the challenges commonly faced with traditional capillary collection. It can be easily used for blood collection without phlebotomy training, and this device consistently and reliably provides a few hundreds of microliters of...

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Additional information

Capillary Blood Collection Products and Sample Transportation Solutions

Greiner Bio-One manufacture and supplies the MiniCollect® capillary blood collection system to a range of customers across the UK including NHS and commercial organisations. The range includes: Capillary blood collection tubes. Lancets. Carrier tubes to aid labeling and processing. MiniCollect® features leak proof caps and can be transported safely.  

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13
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E: A connection is helpful

Capitainer qDBS - sampling you can trust

The Capitainer qDBS sample card is intended for the collection and storing of a fresh whole blood sample of 10 μl as a dried blood spot (DBS). Our products represent world class technology designed for collecting blood at home Passive blood collection in a fixed volume – no additional steps needed by donor or lab Easy to use Convenient and quantitative blood sampling at the fingertip (capillary) for everyone, everywhere at anytime. Enables easy and accurate sampling...

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9
E: A connection is helpful

Cost-effective IgG/IgM test kit. CE Approved

IgG/IgM test kit available from established diagnostic laboratory with over 16 years experience. Cost effective at £6.00/test.

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7
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A: Not for current challenges

Covid 19 antibody testing Kits - As bought by the USA Government - Their order on Friday was for 10m

We can supply up to 5m per week of a highly accurate antibody test kit. Accuracy percentage - 95%, Specificity - 100% - Sensitivity - 95%. 

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9
E: A connection is helpful

Capitainer P

Capitainer produce a microsampling device for the accurate collection of a 10uL blood spot. They also have a device, the Capitainer P, which collects plasma/serum. The device is designed to work with a lancet so blood/plasma can be collected remote to the laboratory and posted back.  https://capitainer.se/

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