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#TestingMethods2020

Catalogue of Resources

49 Ideas
71 Votes
424 Comments
21 Subscribers

The catalogue of resources includes both ideas already distributed via the weekly bulletin and submissions considered useful and are already in the public domain

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Rapid RNA purification and stabilisation by cost-effective lateral flow technology

FloNASep is a simple & rapid biological sample extraction technique for obtaining nucleic acids (including RNA). FloNASep is based on widely-used lateral flow device (LFD) technology and is well-suited to use in the field or at the point-of-care (POC). Please see the product description PDF and take note of the comparable extraction performance with widely-used spin columns.    FloNASep is suitable for extracting, purifying and preserving nucleic acids, antibodies and virus particles...

0 Votes
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D1: Path Lab Bulletin
D3: Catalogue of Resources

Genetic Signatures Automated EasyScreen Assays

Genetic Signatures has recently entered the UK and European market after 5 years of success in Australia building up 30-40% market share in the syndromic testing space with our innovative 3base TM technology. All Genetic Signatures panels run on automated platforms that automate both sample extraction and PCR set-up. The GS1-HT allows processing of up to 96 samples per run in around 2 hours, whereas the GS1000 allows processing of up to 192 samples in around 2 hours (including positive...

0 Votes
4
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D3: Catalogue of Resources

Minimize false negatives: confirm diagnosis with ddPCR SARS-CoV-2 testing

Early reports from Wuhan clinical researchers have shown that Bio-Rad’s QX200 Droplet Digital PCR (ddPCR) System showed superior sensitivity and precision for clinical detection of SARS-CoV-2 compared to existing test methods that are performed using qPCR. The findings suggest that ddPCR can reduce false negative results of COVID-19 without any increase to false positive results, and could be a powerful complement to the current standard of testing. The high sensitivity of ddPCR SARS-CoV-2...

1 Votes
2
D1: Path Lab Bulletin
D3: Catalogue of Resources

Saliva alternative - futher insight

There are actually now several studies that report saliva as an alternative to swabs. Some have used pre-prandial early morning saliva and others have added 'coughing out' (coughing with a closed mouth and then spitting out saliva). May I suggest that as COVID-19 is spread via droplets and aerosols generated from talking, coughing and sneezing that it is likely present in saliva as well as in mucus secretions from the lower and upper respiratory tract. I understand from a discussion I had...

1 Votes
5
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D1: Path Lab Bulletin
D3: Catalogue of Resources

Ultra High-throughput Lab Robotics Systems for RNA extraction, PCR set-up, qPCR & ELISA

Laboratory robotic systems that integrate microplate-based instruments and devices to carry out the automated processing of patient samples for the SARS-CoV-2 antigen and antibody via PCR and serological methods. Fully automated platforms that can be configured to run application-specific protocols with specific throughput requirements. 100,000 tests or more per day is theoretically possible running either a single or group of systems combined. Systems are instrument-agnostic meaning...

1 Votes
7
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D1: Path Lab Bulletin
D3: Catalogue of Resources

virusPHIX™ RNA stabilisation and virus inactivation sample collection tubes

RNAssist is a Cambridge, UK based technology development company focused on RNA stabilisation, pathogen inactivation and cell fixation, our products have been evaluated by 240 researchers including at the University of Cambridge and Oxford, NIBSC, Pasteur, Sanger, CDC and MIT.  Offer; A universal sample collection tube for liquid samples including; blood, plasma, serum, saliva, sputum, nasal mucus, tears, faeces, cells and urine containing  vivo PHIX™ virus inactivation and viral RNA...

0 Votes
4
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D3: Catalogue of Resources

MDBio BCC19 Smartphone based COVID-19 RT-LAMP Test Kit

The Detectachem MobileDetect Bio (MDBio) BCC19 Test Kit is an innovative High Complexity Laboratory test intended for detection of nucleic acids from the 2019-nCoV virus. The test is the latest innovation from DetectaChem, a private manufacturer in Houston, Texas that supplies trace explosive and drug detection platforms to the U.S. Department of Defense, Department of Homeland Security, Department of Justice, State and Local Law Enforcement as well as First Responders around the world....

0 Votes
4
D1: Path Lab Bulletin
D3: Catalogue of Resources

Rapid, high accuracy Covid-19 RNA test to dramatically improve the throughput of testing centres.

This proven technology can deliver a test from swab to result in under 20 minutes (potentially under 10). The system uses a printed electrode to perform a high-accuracy test by binding the nucleic acid of interest to a disposable printed electrode. Each portable test station can perform 20 tests per hour (potentially up to 30) using a relatively low-cost reader and inexpensive consumables. Have you validated this method, if so, how and what were the results of the validation? The...

27 Votes
9
D1: Path Lab Bulletin
D3: Catalogue of Resources

Rapidly increase throughput by using AI to automate interpretation, monitoring and reporting of Covid tests

We have a machine learning system (pcr.ai) for automated interpretation, monitoring and reporting of COVID tests (and any other infectious disease).   Turnaround time (TAT)  is reduced substantially as pcr.ai can send results from any thermocycler to the LIMS in under three minutes. This is a substantial time saving as studies have shown that hands-on-time can be up 85 minutes for new or complex assays and TAT is normally much higher as staff will not always be available to review results...

0 Votes
4
D1: Path Lab Bulletin
D3: Catalogue of Resources

Modular Covid Testing Facilities

Manufacture, Install and Manage Modular Covid-19 Testing facilities as a Turn-key facility, complete with medically trained staff, testing kits and PPE to ease the burden on the NHS and Army whilst providing consistency in testing and return information for analysis. These modules use the very latest Thermal Imaging Cameras that enable people to be pre-screened as well as having the facility for the Anti-body test and the full blood test to be sent away for analysis.The modules are...

0 Votes
4
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