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#TestingMethods2020

Catalogue of Resources

54 Ideas
72 Votes
452 Comments
23 Subscribers

The catalogue of resources includes both ideas already distributed via the weekly bulletin and submissions considered useful and are already in the public domain

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Viral Sign Scanning, Helps identify COVID and Influenza 6-7 days before symptoms appear

We have a technology solution that helps identify COVID 19 and other influenza viruses up to 6 days before symptoms appear. This is the only pre-symptomatic solution on the market. Scan takes 2 seconds to complete. Temperature scanning does not work to identify COVID or influenza in employees that do not show any symptoms. For those people that do show symptoms (including temperature) they can be contagious with COVID for several days before their bodies express it through temperature, thus...

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COVID19 Mobile Testing and Analysis Laboratory

Given the recent (and ongoing) issues with COVID19 testing availability, I thought I would put forward a potentially valuable tool for the government in the fight against the COVID19 pandemic. My business partners in South Africa - Axiology Labs (along with other stakeholders), have developed a fully mobile COVID19 PCR (antigen) and antibody testing laboratory built into a shipping container.  This can be mounted to a regular articulated lorry and taken directly to the areas of greatest...

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D: Ready to share
D2

QIAstat-Dx - Rapid Multiplex Syndromic Testing from QIAGEN

The QIAstat-Dx Analyzer 1.0, in combination with QIAstat-Dx assay cartridges, uses real-time PCR to detect pathogen nucleic acids in human biological samples. The QIAstat-Dx Analyzer 1.0 and cartridges are designed as a closed system that enables hands-off sample preparation followed by detection and identification of pathogen nucleic acids. Samples are inserted into a QIAstat-Dx assay cartridge that contains all reagents necessary to isolate and amplify nucleic acids from the sample....

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D: Ready to share
D2

Direct-to-PCR COVID-19 Testing from PrimerDesign (part of Novacyt) - Exsig Direct

We have already launched our Direct-to-PCR approach (exsig™ COVID-19 Direct). This includes a 5 minute RNA preparation step, followed directly by qPCR for detection of SARS-CoV-2. The process is being CE IVD accredited. Is the method already deployed in a UK hospital or clinical setting? Our original CE IVD COVID-19 qPCR test is already deployed throughout UK healthcare and globally. Exsig Direct has just been launched so will be in place shortly with initial adoption and use currently...

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D1: Path Lab Bulletin
D3: Catalogue of Resources

Genetic Signatures Automated EasyScreen Assays

Genetic Signatures has recently entered the UK and European market after 5 years of success in Australia building up 30-40% market share in the syndromic testing space with our innovative 3base TM technology. All Genetic Signatures panels run on automated platforms that automate both sample extraction and PCR set-up. The GS1-HT allows processing of up to 96 samples per run in around 2 hours, whereas the GS1000 allows processing of up to 192 samples in around 2 hours (including positive...

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D3: Catalogue of Resources

Minimize false negatives: confirm diagnosis with ddPCR SARS-CoV-2 testing

Early reports from Wuhan clinical researchers have shown that Bio-Rad’s QX200 Droplet Digital PCR (ddPCR) System showed superior sensitivity and precision for clinical detection of SARS-CoV-2 compared to existing test methods that are performed using qPCR. The findings suggest that ddPCR can reduce false negative results of COVID-19 without any increase to false positive results, and could be a powerful complement to the current standard of testing. The high sensitivity of ddPCR SARS-CoV-2...

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D1: Path Lab Bulletin
D3: Catalogue of Resources

Saliva alternative - futher insight

There are actually now several studies that report saliva as an alternative to swabs. Some have used pre-prandial early morning saliva and others have added 'coughing out' (coughing with a closed mouth and then spitting out saliva). May I suggest that as COVID-19 is spread via droplets and aerosols generated from talking, coughing and sneezing that it is likely present in saliva as well as in mucus secretions from the lower and upper respiratory tract. I understand from a discussion I had...

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D1: Path Lab Bulletin
D3: Catalogue of Resources

Ultra High-throughput Lab Robotics Systems for RNA extraction, PCR set-up, qPCR & ELISA

Laboratory robotic systems that integrate microplate-based instruments and devices to carry out the automated processing of patient samples for the SARS-CoV-2 antigen and antibody via PCR and serological methods. Fully automated platforms that can be configured to run application-specific protocols with specific throughput requirements. 100,000 tests or more per day is theoretically possible running either a single or group of systems combined. Systems are instrument-agnostic meaning...

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D1: Path Lab Bulletin
D3: Catalogue of Resources

virusPHIX™ RNA stabilisation and virus inactivation sample collection tubes

RNAssist is a Cambridge, UK based technology development company focused on RNA stabilisation, pathogen inactivation and cell fixation, our products have been evaluated by 240 researchers including at the University of Cambridge and Oxford, NIBSC, Pasteur, Sanger, CDC and MIT.  Offer; A universal sample collection tube for liquid samples including; blood, plasma, serum, saliva, sputum, nasal mucus, tears, faeces, cells and urine containing  vivo PHIX™ virus inactivation and viral RNA...

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D3: Catalogue of Resources

MDBio BCC19 Smartphone based COVID-19 RT-LAMP Test Kit

The Detectachem MobileDetect Bio (MDBio) BCC19 Test Kit is an innovative High Complexity Laboratory test intended for detection of nucleic acids from the 2019-nCoV virus. The test is the latest innovation from DetectaChem, a private manufacturer in Houston, Texas that supplies trace explosive and drug detection platforms to the U.S. Department of Defense, Department of Homeland Security, Department of Justice, State and Local Law Enforcement as well as First Responders around the world....

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