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COVID Plus : Multiplexing with other pathogens

17 Ideas
0 Votes
38 Comments
26 Subscribers

As we move towards the winter flu season, we must consider how to include COVID 19 viral detection into the wider respiratory virus and/or gastrointestinal virus testing regimes. We are seeking testing kits that will deliver multiplexed or syndromic respiratory and/or gastrointestinal viral detection and that will operate on either existing rapid turnaround laboratory platforms, existing near patient care platforms or new technologies that can be deployed into NHS and PHE testing laboratories. These should be ready to deploy within 4-6 weeks.

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Viasure Flu/RSV/COVID Multiplex RT-PCR

Pro-Lab Diagnostics is launching a novel Viasure multiplex RT-PCR kit targeting influenza (A,B,H1N1), respiratory syncytial virus (A,B) and SARS-CoV-2 (N1,N2), with an RNase P endogenous control. The Viasure range of RT-PCR kits are lyophilised room temperature storage with a simple 2-step test procedure. The SARS-CoV-2 kit is used widely in the UK and world wide with over 6 million tests supplied to date. Production capacity for the UK currently runs at 1 million tests per week with...

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B: One to watch

Breath of Health

Our innovative technology Is based on well established research of groups of chemical markers, that are generated in certain stages and progression of air infectious diseases and can be corelated to specific causing effects in regard to other clinical conditions incorporated into our algorithms. These can be grouped and cross related of Ketones, Proteins and radicals, and possibly other marker groups such as lipids, fatty Acids etc, we expect to identify can be identified easily enough in...

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posted twice in error - see direct-to-pcr post

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B: One to watch

GeneFirst multiplex respiratory panels for high-throughput and POC testing

GeneFirst, using its patented MPA (Multi Probe amplification) technology, has developed a respiratory pathogen panel (RPP) to help in the detection of various respiratory pathogens in an easy to use, one closed-tube assay. The panel detects 11 respiratory viruses (Adenovirus, Influenza (A and B), Parainfluenza (1-4), Rhinovirus, Respiratory Syncytial Virus, Bocavirus, Coronaviruses (-229E, -HKU1, -NL63 and -OC43) and 2 bacteria (Chlamydophila pneumoniae, Mycoplasma pneumoniae). We have...

2
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B: One to watch

Randox Discovery: High Throughput, Fully Automated Molecular Diagnostics Analyser

The system utilises ready to use cartridge based prefabricated reagents. Up to 16 patient samples can be run in a single batch, and using Randox Biochip Array Technology, multiple targets can be detected simultaneously in each specimen. The machine is comprised of three interconnected modules with the first module performing sample extraction and purification, the second conducting multiplex PCR and the third module managing biochip hybridisation and detection. First results are reported...

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B: One to watch

The Rapid MiniLab Multi-Pathogen RVP / SARS-COV-2 Test

Looking forward, anticipating the next emerging threat and improving our current testing methods, we have developed a saliva sample Covid-19 PCR test and separately developing a multi-pathogen RVP/Covid-19 test based our existing CE marked RVP assay. The existing RVP assay is an automated multiplex PCR test for the simultaneous qualitative detection of Influenza A, Influenza B, Respiratory Syncytial Virus (RSV) and Rhino Virus. This test uses nasopharyngeal swab specimens. The RVP /...

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D2

AB Molecular – GenMark ePlex® Multiplex PCR Respiratory Panel and SARS-CoV-2

GenMark Responds to the SARS-CoV-2 Outbreak On March 19, 2020, GenMark Diagnostics announced that the U.S. Food and Drug Administration (FDA) has issued Emergency Use Authorization (EUA) for the company’s ePlex® SARS-CoV-2 Test. Read our  press release  to learn more. The ePlex SARS-CoV-2 Test is an automated qualitative nucleic acid multiplex assay designed to detect SARS-CoV-2 nucleic acid in nasopharyngeal swabs collected in viral transport media. This test is performed on the...

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C: Further assessment

Respiratory tract microbiota by Applied Biosystems | Thermo Fisher Scientific

Our real-time PCR solution for respiratory tract microbiota (RTM) is a rapid, sensitive and flexible-content solution for the detection of respiratory pathogen targets. *Extensive coverage of up to 42 pathogen targets and also SARS-CoV-2 targets *Flexibility and customization according to your needs *Fast results and cost-effective *Multiple sample input types

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C: Further assessment

FebriDx - Rapid POC Viral vs Bacterial test

FebriDx is a rapid, all-in-one point-of-care test that can differentiate viral from bacterial acute respiratory infections.  FebriDx has high sensitivity for the identification of COVID-19 infections and can be deployed as a front door triage test in the Emergency Department and other healthcare settings. In two UK hospital studies FebriDx was shown to be highly accurate to rapidly detect and triage patients with Acute Respiratory Infections, overcoming the current issues of delayed...

1
C: Further assessment

GenMark Syndromic Multiplex Rapid Respiratory Testing

GenMark have a respiratory panel with 20 viral and 4 bacterial targets that runs on a single use cartridge. We are working on an updated version of this panel that will include our current single target SARS-CoV2 target and which will run on our ePlex system in around 90 minutes also. GenMark's ePlex system is a scalable bench top solution available in a 3 bay, 6, 12, 18 or 24 bay format. Each bay works independently and offers random access with true walk away technology from inserting the...

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