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3G-202 virus sample preservation solution kits

A: Not for current challenges

Goldlane Ltd acts on behalf of NKY Medical Holdings (a company listed on the Shenzhen stock exchange) and their subsidiary 3G Biotech. Our virus specimen preservation solution kit provides for reliable and high quality RNA preservation and safe transportation. Samples taken by nasal or throat swabs can be safely transported at ambient temperature with minimal specialist equipment. The sample preservation solution stabilises the nucleic acid to be tested, improves the concentration of the sample, and provides better quality assurance for the nucleic acid testing of the sample by effectively inactivating the virus, and inactivating any nuclease present.

Have you validated this method, if so, how and what were the results of the validation?

The use of highly denaturing conditions is known to destabilise the viral envelope, eliminate cellular nucleases, and maintain the structure of RNA for later analyses. Our preservation solution is composed of guanidine salts (guanidine thiocyanate, guanidine isothiocyanate), which have been proven to be efficient for the inactivation of enveloped RNA viruses.

How quickly could this be deployed and what are the dependencies?

Our sample preservation solution kits are already being produced and production can be scaled up rapidly to meet contractual terms. 

What is the likely production volume?

We can provide 150 litres of preservation solution per day, which is sufficient for 50,000 samples per day (sample collection and transportation tubes provided ready to use).

What are the risks and barriers to using this at scale?

Samples need to be purified before amplification.

Who are you already partnering with on this?

Already supplying to a UK-based pharmaceutical company (more details available on request).

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Bev Matthews Apr 21, 2020

The idea has been progressed to the next milestone.

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Sue Hill Apr 21, 2020

has this been used and validated with COVID 19

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Graham Parker Apr 22, 2020

Yes. 3G-202 has been used widely by hospitals and medical laboratories in China as part of their COVID19 response actions.

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Bev Matthews Apr 21, 2020

Status label added: Requires more information

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Bev Matthews Apr 25, 2020

Status label removed: Requires more information

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Bev Matthews Apr 26, 2020

Status labels added: D, E

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Bev Matthews Apr 26, 2020

Thank you Graham, your solution has been reviewed. i need to get additional information to complete this review so will come back to you next week. Bev

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Graham Parker May 6, 2020

Dear Bev - do you need further information from us? We are ready to provide it to help you complete the review.

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Bev Matthews Apr 26, 2020

Status label removed: E

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Bev Matthews Apr 29, 2020

Status label added: C: Further assessment

Status label removed: D: Ready to share

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Tom Jordan Jul 23, 2020

Status label added: A: Not for current challenges

Status label removed: C: Further assessment

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